Entropic thermodynamics and aging

December 11, 2013

Entropic thermodynamics and aging

In its homeostatic aspects, biological life follows the universal laws of thermodynamics.
The processes of biological aging are characterized by an increase in entropy and a subsequent structural disorder.  Consequently, the self-repairing system of our cells becomes less efficient through the poor use of energy and an accumulation of damaged heterogeneous material that accelerates the process of aging and its consequent diseases.
We must consider our organism an open  microcosm in constant connection to the external macrocosm.

The physics of the universe has a constant interchange with the physics of our biological systems, through very refined energetic mechanisms that exchange heat and matter.  In this way, the free, available energy at the cellular level and at the connective matrix is directed towards the formation or the reparation  of the structures necessary to the correct functioning of the cells themselves.  Life is made possible through an ensemble of physical and vibrational processes that regulate the physiology and metabolic chemistry of the body, contrasting the increase of entropy expected from the II law of thermodynamics.

The damaged matter derives mainly from the mitochondria and mitochondrial DNA.  Mitochondria have a fundamental role in the aging process and in the maintenance of homeostasis as it is in these areas that 95% of the ATP of the organism is produced through cellular respiration.   The damaged mitochondria activate the immune system and activate the inflam-aging process, a chronic inflammation that alters the citochine system and accelerates aging.  The problem of the production of necessary energy is fundamental to the understanding of the events that regulate aging;  in the irregularity and apparent disorder there is a hidden order and this complexity furnishes the body-mind system a set of information.  If this system loses its harmony because of an interaction between psychological, biological and environmental factors, the processes of aging are activated.