A randomized study conducted at the Barts and the London School of Medicine and Dentistry, London, and published online November 24, 2014 in Hypertension, found that daily administration of nitrates food in the form of beetroot juice significantly reduced blood pressure high compared with placebo in patients with hypertension for more than four weeks.
The researchers have observed a significant reduction in systolic and diastolic blood pressure among patients who drank 250 ml of juice per day, for a dosage of nitrate of about 6.4 mmol / day.
The same amount of beet juice, but depleted of nitrates, is served as a placebo.
Were observed improvements in endothelial function and arterial stiffness also in the food group with nitrate than the placebo group in the different parameters of controls.
The results suggest a role for nitrate food as a tool readily available in the adjunctive treatment of patients with hypertension.
All patients completed dietary interventions for the duration of the study. Hypertension was confirmed by ambulatory blood pressure monitoring (ABPM) for enrolment of study in all patients.
The dietary consumption-nitrate has been associated with a decrease in blood pressure in clinical by ABPM to 24 hours, and the readings at home in the group of beet juice compared to baseline.
No change in blood pressure on each of the three measurements was observed between the placebo controls.
The administration of inorganic nitrate in the diet raises levels of circulating nitrite and DI tissue through a bioconversion in circulation enterosalivary.
We know that nitrite is a potent vasodilator in humans and supplementation of dietary nitrate as used in this study has led to an increase of about 5.5 times of nitrate concentrations in the plasma while the plasma concentrations of nitrites were elevated about 2.7 times the baseline.
A good hope accompanying the antihypertensive therapy.