The Physiological Regulating Medicine (PRM) born by a idea: restore Physiology through molecules such relationship hormones, interleukins, growth factors and neuropeptides in low physiological dose, which correspond to the same concentration at which they are present at the level of trans-membrane receptors in the matrix extra-cellular.

The pivot of the Physiological Regulating Medicine are the messengers molecules, that are the messengers, the words used by the three major homeostatic control systems to “talk” to each other. The importance of the connective tissue in medicine physiological adjustment is given by its functionality and composition; so, it is understood as a unit “morpho-functional” comprising the capillary network, the matrix and the membrane receptor.